Cytochalasin A 是细胞可渗透的真菌毒素,是细胞松弛素 B 的氧化衍生物。Cytochalasin A 是 HIV-1 蛋白酶的抑制剂 (IC50=3 μM),抑制肌动蛋白聚合,并通过与巯基反应干扰微管组装。具有抗生素和灭真菌活性。
生物活性 | Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC50=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives. |
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分子式 | C29H35NO5 |
分子量 | 477.59 |
CAS号 | 14110-64-6 |
中文名称 | 细胞松弛素A |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |